with ammonium chloride (NH4Cl) in 23 clinically normal
cats. The concentration of hydrochloric acid (HCl)-insoluble
sediment, urine pH, struvite activity product (SAP), number
of struvite crystals in urine, and urine volume were all
measured.
Diets containing either 29% crude protein or 55% crude
protein were fed to cats in a crossover trial of 3 weeks/period.
Diets supplemented with either sodium chloride (NaCl)
or NH4Cl were given.
The
investigators have concluded that compared with dietary
supplementation with NH4Cl, the high-protein diet is preferable
as a urine acidifier for the prevention of struvite crystal
formation in clinically normal cats.
Reference
Am J Vet Res. 2003 Aug;64(8):1059-64. Effects of a high-protein
diet versus dietary supplementation with ammonium chloride
on struvite crystal formation in urine of clinically normal
cats. Funaba M, Yamate T, Hashida Y, Maki K, Gotoh K,
Kaneko M, Yamamoto H, Iriki T, Hatano Y, Abe M. Laboratory
of Nutrition, Azabu University School of Veterinary Medicine,
1-17-71 Fuchinobe, Sagamihara 229-8501, Japan.